Anything with van Damme or Seagull in*, Sly films comes pretty close too.
But without a doubt in my mind Eraserhead is probably the weirdest and worst film I've ever had the misfortune to (try to) watch.
Also up there are most US remakes of European or Japanese films, just because some people don't like reading subtitles and most dubbing is crap.
*Unless it has Erika Eleniak jumping out of a cake, obviously.
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