If it is a kinetic penetrator only, it is doubtful. Like an HE round from a tank getting through steel plate.
Shape and weight are factors in penetration. (Knock it off, Dowly
) Also, there is no reason the fuse or warhead has to be in the front of the munition.
Possibly a multi-stage munition? Ever see camera footage of a double bomb strike? The first bomb clears a path for the second to penetrate to the target before the debris cloud can settle? Be interesting to see if that would be possible with a single big munition.