The 250 Gig hard drive is the only concern. Especially if you want to use the supermods.
If your case will hold another hard drive, I would go and snag a 1 or 2 TB hard drive and install it. With all the mods out there, it wouldn't hurt to have a second one with a huge capacity, as some of the mods are rather extensive.
Check out the comments on the ATI 3200 graphics here,
http://www.tomshardware.com/forum/25...graphics-rs780
That could pose an issue. So you can try it, but one of the comments said that anything below the 3850 was not good for gaming.