Quote:
Originally Posted by Skybird
He is the office holder. 
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Still has to be nominated by the Party.
Bobby Kennedy and Hubert Humphrey both ran for the Democratic nomination for 1968 while LBJ was in office (although LBJ was not seeking a second full term).
In the 1976 Republican convention Reagan challenged incumbent president Jerry Ford and nearly won. Ford would then lose to Carter in the general election.