@privateer
Hi mate, and thanks for the help. Ok here comes the extra info you asked for.
Sys Specs
Win7 64 bit (UAC disabled) (All non-essential services closed using Game Booster 3)
Intel i7 920 @4GHz (also tried running @ stock clock - no change)
12G corsair ram
2xSeagate Barracuda in raid0
1x Intel 80GB SSD
EVGA GTX580 1.5 GB
Using the 4GB patch.
(If you need driver info/dxdiag info I can supply that, didn't want to bog the thread down)
------------------------
Activated mods :
Generic Mod Enabler - v2.6.0.157
[D:\Program Files (x86)\Ubisoft\SilentHunterIII\MODS]
GWX - Captain America's Officer Icons
GWX - Integrated Orders
GWX - VIIC41 Player Sub
LifeBoats&Debris_v4
GWX_DFa-Flag&Pens_2010
FM30_UpDown_final
FM_NewInterior_V1.0
Conning Tower open Hatch TestFMfood
Depthcharge Shake v2.01
Urfischs_ModStrike_Beta1
Waterstream+Exhaust Combi V2.3 for GWX3
New Uboat Guns 1.2
Real Depth Charge
Searchlights_Removed
Torpedo damage Final ver2.0
Foam
WAC4.1 SubPen_animated_18.02.2010
Combat Radio Frequency
Flags_enlighten
Fubars Das boot VIIC
TiefeMkI(German)
Rapt0r's Uniforms V2.0 [Grey]
No Medals On Crew [Patch]
GWX 3 Wilhemshafen,St Naz,Schluese and xtra ships V6
Q Ship mod GWX3.0
Derzeitige Tiefe
konrad krumms type 7c
b25_ConningTower_Mid
Kaleun's Cap
Wooden_Lifeboats_Mod_1.1
Destroyers&Corvette
Materials file for Aces' multi-mod v1.3
DD_VisibleMines_V1.0
Torpedo_HAHD_1024_GWX
GWX3.0 All_Weather_Guns
GWX - Late War Sensors Snorkel Antennas
Thomsen's Sound Pack V3
PT_SoundPack_V3.1
SH3 Gramophone
Karle's_Crash_Dive_Mod
Merchant_Fleet_Mod_3
Aces' Multimod compatability fix release v1.3 public beta
Aces'_Multimod_Fix_v1.3_Johann_add-on
Aces' Radio Room Postcards
SH-5 Water for GWX 3.0 V0.8 20 Km Atlantic campaign (default)
Sobers_3d_Waves
Subphones
Aces' Super Turms v5.1 GWX Version
Aces' Super Turms v6 for GWX
Aces' Super Turms v6 Damo's Type 7 Atmospheric Interior lighting add-on
Aces' Super Turms 5.1 FM's Turm 7c2 Lightmaps add on
Aces' Multimod compatability fix FM's Turm 7c2 Lightmaps add on
b25_SF_Grass_Full_V2
WB's Renown Replacement
PT_SoundPack_V3.2
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Campaign info:
Patrol 6, 21:22 hrs, May 28, 1940
13km north Dunkirk.
--------------------------------------
Here comes the usual crash log:
Problem signature:
Problem Event Name: APPCRASH
Application Name: sh3.exe
Application Version: 1.4.0.1
Application Timestamp: 42ae9b3e
Fault Module Name: SH3Collisions.act
Fault Module Version: 0.0.0.0
Fault Module Timestamp: 42ae9a2a
Exception Code: c0000005
Exception Offset: 00009d20
OS Version: 6.1.7601.2.1.0.256.1
Locale ID: 2057
Additional Information 1: cda8
Additional Information 2: cda8483c32154a9f3a892cb29fc2293d
Additional Information 3: 7e37
Additional Information 4: 7e37e074d90e8533915c18ce725512e6
--------------------------------------------------------------
Addition to this is, on trying to load my save to get the relavent info for you. I had subsequent crashes at different time periods, anything from straight after 'A Long Time...........' , to a couple minutes after the patrol continues. Second crash log as follows:
Problem signature:
Problem Event Name: APPCRASH
Application Name: sh3.exe
Application Version: 1.4.0.1
Application Timestamp: 42ae9b3e
Fault Module Name: StackHash_cda8
Fault Module Version: 0.0.0.0
Fault Module Timestamp: 00000000
Exception Code: c0000005
Exception Offset: 00000033
OS Version: 6.1.7601.2.1.0.256.1
Locale ID: 2057
Additional Information 1: cda8
Additional Information 2: cda8483c32154a9f3a892cb29fc2293d
Additional Information 3: 7e37
Additional Information 4: 7e37e074d90e8533915c18ce725512e6
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Cheers privateer. Hope this helps solve the problem mate, as always any help is really appreciated. 
Best regards.
Fubar2Niner
PS. Sorry for the excrutiatingly huge post 