The problem is either not enough CPU, not enough RAM and/or overheating. If you are running windows7, you should have a minimum of 4 Gb RAM, and should use the 4GB switch. In addition, you can use a RAM maximizer such as Game Booster or AlacrityPC.
Several mods are RAM hogs; you should experiment by running with various mod setups.
Fish in the water's suggestions as to reducing the campaign files might be the only thing you must do but, as far as I know, this only works with GWX3.0.
Turning down the graphics in the options might help also.
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Irish1958
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