As an IT person that deals with this every day, my favorite is actually X-Cleaner.
http://www.majorgeeks.com/download3034.html
It can run from the web but I like to save it on my hard drive and not have to do an install. The freeware version can really zap just about everything.
The key to making this or any other spyware cleaner work is knowing what exe files that are spyware are running and then to stop them from running by using procexp.exe:
http://www.sysinternals.com/Utilitie...sExplorer.html
-my 2 cents