Personally, I put the realism at 100% (after configuring the setting values), just so I'm not tempted to teleport back home, for three reasons: 1) real crews never had that luxury, and puttering around the ocean being bored took up the majority of their patrols; 2) when I just teleport back to port, I don't have the same sense of accomplishment that I do when I stick it out through the entire patrol; 3) since I can't teleport, the chances of me seeing a ship on the return trip are 100% higher than they would be otherwise
This is just me though, and after a while it does get tiresome. Then I just remind myself that I'm compressing weeks, or even months, of misery and boredom (and some terror) into two or three hours of staring at a computer screen. Those guys must've been absolutely batsh!te insane when they returned to port