If you have any mods installed, it is recommended that you patch to a fresh installation... if for no other reason, than if you have problems, then SCS can't say: "well you've got the such and such mod installed, so we really can't help you."
Honestly, it shouldn't matter if you have our mod installed, but other mods like the font mod and sound mods and the like might cause problems.
So, bottom line, is: if you DW is totally stock, then you won't have to reinstall, most likely.
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LW

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