Alright, first things first.
Backup your registry, perform a recovery disc for the system and a bootable repair disc.
Next, you need to install a virus scanner on your computer, like nortons 360 just as I did.
Next, defrag your hardie, and make a recovery partition if not already made.
Now comes your issue, the mods. Did you put JSGME? installed it to SH4 root folder?
How about this, uninstall the game fully and a clean reinstall as described
here
Check each mods readme/changelog, and see if it conflicts with the other desired mods. If not available, browse through the mod directory and compare the files on both mods. Maybe one overwrites the other without you knowing or it telling.
I wish you the best experience with your new laptop and keep us posted for anything else.
Regards,
CS2K9