Unfortunately corrupted savegames are a known issue with the game that has not yet been resolved.
The general consensus is that you'll have a better chance of avoiding them if you do not save submerged or within contact distance (visual or on the hydrophones) of any other units - planes, ships, whatever. Another rule of thumb is not to save when you are within 50 km of other units or land, but personally I've never had a problem just by following the "can't see 'em, can't hear 'em" rule.
It's also recommended that you not change any mods unless you are safely docked somewhere in between patrols or missions.
Even if you are very careful to follow those recommendations, though, sometimes bad saves just happen. If you have earlier saves you can try loading them, working backwards chronologically, until you find one that's good, and play from there.
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