hopefully you installed all your mods with jsgme, if so its any easy fix.
what you have is a corruption of the game files and if it was done with jsgme then read the "mod soup fix" in my sig to fix it.
if you were doing some modding of your own then the corruption can only be fixed by replacing the corrupted file (only if you know for sure what file it is) or a clean reinstall of the game after uninstalling and deleting any remaining leftover files
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