This may probably not be very helpful, however, SH3 was not running for me on Vista either. I have the same Dell than Von Manteuffel and was having lots of issues with Vista (app running slow. app not working) that I decided to go for Win7.
Since then I am a much happier person, everything runs without me doing mumbo jumbo and sacrificing chickens.
I know Bernard likes vista, but don't listen to his whining.
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