No.
You can not add to or remove from existing meshes.
Anything that would change the actual file size is a No No.
Granny has a table built in that I have not figured out yet.
That table tells Granny where everything is.
Change the file size and you've moved things.
What probably/maybe/hopefully can be done is a work around that I can not test.
Say you want to control a needle on a dial in a mesh.
You move the placement of that needle so it does not show.
Then add a new 3D needle in one of the other files.
Add the needed controllers to it.
Then test the theory.
Not being able to run the durned Game?
All I can give you is ideas.