Strange - I've been running with synch ON ever since March and as far as I can tell have never had any problems with it (certainly not like those noted above) with either my 6800GT or my X800XL. Certainly seems worth a shot disabling it though if you're having problems and seeing if it makes a difference - I've never really tried turning it off to see if I could tell the difference, but since it ain't broke (for me at least) I don't think I'll try "fixing" it just to satisfy that curiousity.
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