I have a corei7 920 running 3.4ghz and a gtx295.
I get the stuttering too and I have to run alternate frame rendering 2 in the drivers or sh5 only uses 1 gpu.
I have it running 1920x1200 with all settings on except shadows off.
Shadows seem to make it really bad.
I hope a sli profile is released but I doubt it.
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