Quake's BFG can suck on the Unreal Tournament's Redeemer
The Redeemer is just hilarious...the thing caused insane damage and with a packed server you could unleash the M-m-m-m-Monsterkill kil kill
it pissed players of when in use, and seeyin people trying to run from it...
my list of favorite weapons per game (the ones I can recall) are:
PC:
UT: Redeemer
Quake3: Railgun
Medal of Honor: Allied Assaul: Mauser
Call of Duty (1st one): Kar98/Mosin
HL: Crowbar
HL2: Gravity gun
TF2: Heavy's Minigun
BF2: L96A1 Sniper Rifle
ArmA: Satchel charges / G36 family
Doom: Chainsaw
Duke Nukem 3D: Mighty Boot!
Nintendo 64
Goldeneye: Magnum
Perfect Dark: the Tranquilizer (turning your friend's screen in Splitscreen mode to a blurry mess is fun
)
Turok: Rage War: Inflator gun
HunterICX