No, AFAIK all works perfectly in GWX3 with Indian Ocean.
That said, be ready for a very different way of playing. You will be moving around in a big, slow, clumsy U-cruiser, and you better stay away from escroted convoys and areas with lots of aircraft patrolling (Indian coast and Ormuz Strait as well as Cape Town and major Ozzie cities).
Good luck and good hunting
