If you have any doubts about March of Dimes, take a look at their history. The charity was founded by FDR to eradicate polio, and within 20 years March of Dimes funded research had produced a polio vaccine. They're one of the only charities I know of that was completely successful in achieving the goal that they were founded for.
After their success against polio, they turned to premature birth. If they can be half as successful in that fight as they were in the polio fight, they will have done a lot for the world.
Kudos to GR, his wife, and everybody else that supports this very worthwhile and effective charity.
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