I use EndItAll when I need to terminate processes in one keypress. But I'm able to run SH4 at decent framerates with a truly scary list of programs running in my tray.
It's not impossible for another program to steal enough clock cycles to kill your framerate, but it's likely to be a single application doing that. Tell you what.
Alt-tab out of SH4. Press ctrl-alt-delete and bring up your task manager. Choose the processes tab and check out the CPU column, which shows the percentage of CPU utilization by process. System Idle Process is not a true process, but unused clock cycles, so disregard this. Is any other process hogging your CPU? You can terminate it right from Task Manager. Chances are you won't find any guilty parties there and will be back to eating mod soup. Yum!
