Thanks for the info on the gap depth scales mod. But when I try to put NewUIs before OHII, i get that damn screen mess. Ugh!

Open up the Generic Patcher and read all the patch notes (Notes= and Files=) of each patch you have enabled. Double click them to view if they don't say None

Almost all of them have none in both fields (mostly the bugfix patches). Some have some files e.g. the independent engine controls but no notes.

I focused specifically on the torpedo patches. From what I've seen, only the following patches have something in the files section but nothing in the notes section. I tried double clicking, no effect.

From SHSim Torpedo patches:

1. Torpedo premature chance fix
2. Torpedo circle runner calculation
3. Torpedo gyro problems chance fix
4. Torpedo gyro deviation calculations
5. Torpedo depth keeping problems fix
6. Torpedo impact angle fix
7. Torpedo dud chance fix

I used the torpedos set to impact detonation exe patch and also chose the option in the UI options application, is that causing problems?

EDIT: I was experiencing this condition when i used an alternative mod order (see post no. 17), its possible with the new mod order (post 24) this issue will go away. I haven't been able to test yet as i experienced a CTD before encountering anything in the first patrol

Newer EDIT: The issue is still there. Just tested the TDW Tutorial mission. 5 out of 6 torps were circular runners. both with manual and auto TDC

Update: I cut out the crew uniforms mod and the updated depth scales mod (the gap one) and now I can start the campaign. Still, suffered a CTD on the first patrol. This is the current mod order and list:

Accurate German Flags
sobers game loading tips SH5
DBM Background Video
SteelViking's Interior Mod V1.2
SteelViking's Interior Mod V1.2.2 Patch
sobers multi color mod V5
DynEnv v2.9 - 1. Main Mod
DynEnv v2.9 - 5.c Ambient Settings - Darker Nights-No Murky Waters
DynEnv v2.9 - 6. Sleet for Winter Campaigns
DynEnv v2.9 - 9. Sobers Best Ever Tweaks
DynEnv v2.9 - 12. Sounds
Small_trees_SH5_V1
sobers smoke screen V1 SH5 (DynEnv compatible)
sobers water splash anim SH5
sobers best ever fog V22 SH5
sobers base sky mechanics V1
sobers better terrain v3 SH5
SH5_7A_Conning_Fix
Fuel Gauge WoGaDi_SteelViking's Interior
Equipment_Upgrades_Fix_v1_4_byTheBeast
Equipment_Upgrades_Fix_v1_4_Patch_1
Equipment_Upgrades_Fix_v1_4_Patch_1 (available by date) V9 by sober
#Equipment_Upgrades_Fix_v1_4_Patch_1_HotFix
EUF_UBoat_FX_v0_0_3_ byTheBeast
SH5 Longer Repairs v.1
AI_sub_crew_1_0_2_TheDarkWraith
FX_Update_0_0_21_ByTheDarkWraith
NewUIs_TDC_7_4_2_ByTheDarkWraith
NewUIs_TDC_7_4_2_alt_officer_wounded_by_Torpedo
NewUIs_TDC_7_4_2_ERM_Reaper7_NightVision
NewUIs_TDC_7_4_2_RadCapTools_0_2_alpha
Sjizzle's - Charts for NewUIs part1_07.06.2013
Sjizzle's - Charts for NewUIs part 2_07.06.2013
Sjizzle's - Charts for NewUIs part 3_24.06.2013
Sjizzle's - Charts for NewUIs part 4_20.07.2013
Manos Scopes-patch for 16x9
KZS Hull wetness for U-Boats + co tower and deck_revised_by_TheDarkWraith
IRAI_0_0_39_ByTheDarkWraith
IRAI_0_0_39_Inertia_Damage
R.E.M_by_Xrundel_TheBeast_1.2
R.E.M_by_Xrundel_TheBeast_1.2 - no hyd on surface - NewUIs-IRAI compatible
Depth Charge Fix Reduced Explosion Range
Cerberus62 Corrected Depth Charge Projector 1.0
NOZAURIO'S SKIN (Standar No Emblem) v-1.1.0
OPEN HORIZONS II_full v2.2
SkyBaron's Leigh Light for SH5 1.1
TDW_Mines_Subnets_Detectable_in_hydro (OH II v2)
TDW_Ship_Inertia_1_1_0
TDW_Updated_RadioMessages_English
Sobers Terrain fix for OH2 V2.2
Expanded Navies by Cybermat47 v.1.0.0
Fix clock rear torpedo room VIIA
Reworked Morale and Abilities v.1.1
MightyFine Crew Mod 1.2.1 Alt faces
MCCD_1.04_MFCM_1.2.1_compatible
MightyFine Less Annoying Footsteps 1.0
Speech fixes and additions (english version)
RPM Hydrophone v2.2 -for OHII full v2.2-
sobers green crew training V4 SH5
TDW FX Fix for Sobers chimney smoke
Church's Compass Dials Mod v2.2 - Option Two
smaller flags for Warships 1_0b
sobers Lights Cfg V5 SH5
Stormys DBSM SH5 v1.3 Basemod
Stormys_DBSM_additional_creaks_and_noises_1.0
Grossdeutscher Rundfunk
ASDIC_alternate_sound
Trevally Tutorial - All v0.2(for OHIIv1.3)
Trevally Automated Scripts v0.6
Trevally Harbour & Kiel Canal Pilot v3.1
sobers hud sounds V1 SH5
sobers_realistic_underwater_FX3
EQuaTool 01.01 by AvM - Large Style
AOB slide ruller for TDW UIs and MO by stoianm
gap - HD 1 deg Scope Bearing v 1.0
gap - Sonar Sound Collection v 1.0 for SH5 - Distorted
Shadow Improvement ModLR
OH II Minefield map for TDWs Ui
Window_Lights_Redone_V1
sobers bad weather deck gun V5 SH5

Looking at your mod soup you are missing the mod
FX Update torpedoes (modified for torpedoes failure patches)

Within your extracted TDW_GenericPatcher folder you'll find a MODS folder. Within this MODS Folder you'll find a

All the torpedoes modified for torpedoes failure patches (GenericPatcher add-on).7z file
Decompress this file and youl have 4 Mods

FX Update torpedoes (modified for torpedoes failure patches)
FX Update torpedoes - MagDet range 3m (modified for torpedoes failure patches)
Stock torpedoes (modified for torpedoes failure patches)
Stock torpedoes - MagDet range 3m (modified for torpedoes failure patches)
and a readme.txt

active one of the four mods
the first or second named "FX Update torpedoes..." have to be after
FX_Update_0_0_21_ByTheDarkWraith which is listed in your mod soup as stated in the readme file.

with doing so you'll have realisic torpedo failures but not mentioned 5 out of 6

I had a similar mod list when I had CTDs. One or both of the intertia mods is not needed anymore. The inertia problems and CTDs was discussed under the threads of open horizons, or sober's mod list, or TDW SH5 patcher or Multi UIs for SH5. I started a new game in the bunker and all of a sudden I am getting CTDs after updating the mods list.