You can't really do any harm . The key bindings in the Options file viewer are limited to Keyboard Keys as best I remember . the other settings just set to false if you don't want a combination of Keys
Another option is a mouse with extra customisable/editable buttons like a Logitec , mine was pretty cheap had it for years . No need to use options file viewer
I'm not sure what you are trying to achieve if you are using a normal generic mouse controlling the sub that way would be extremely limited .
I may be missing the point what would be the advantage for you ?