Running SBP myself, can confirm that 2.552 and 2.640 run reliably under Win7 x64 Pro.
x64 also is no issue in their support forum, there were occasional questions, but afaik nothing serious that remained unsolved.
To be sure, run it as administrator.
Upgarding from Vista to W7 and X32 to X64 is highly recommended. Vista was bad, W7 is nice.
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