Alt+tab usually doesnt make the TIR to not work. I've had some occasions where the TIR has though the game is still running even if it isnt, so when you start the game the TIR doesnt start properly and it wont work. This can be solved by quitting & restarting TIR. Just check the lights in the TIR before you start the game, if the blue (or whatever the color is when TIR is in game mode) on is on, then you need to restart it.
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