Thanks Frinik.
What is strange is that it ran before fine with the same soundcard.
In desperation I booted up my Win XP disc and installed it to there and guess what? Yes,still won't run so I guess there is some sort of conflict between the GTX 280 and the Asus Zonar D2X soundcard.
At this rate I will have to pop the ATI back in.
I will have to walk away now,I need to rest.Maybe have another go tonight.